150988-80-0

150988-80-0 structure

Name: Bupropion D9
Chemical Name: 1-(3-chlorophenyl)-2-[[1,1,1,3,3,3-hexadeuterio-2-(trideuteriomethyl)propan-2-yl]amino]propan-1-one
CAS Number: 150988-80-0
Molecular Formula: C₁₃H₉D₉ClNO
Molecular Weight: 248.79700
Catalog: Signaling Pathways GPCR/G Protein Dopamine Receptor
Create Date: 2016-10-28 14:06:12
Modify Date: 2025-08-24 23:07:58
Bupropion D9 is a deuterium labeled Bupropion. Bupropion is an atypical antidepressant of the aminoketone group and inhibits dopamine, norepinephrine reuptake and blocks several nicotinic receptors[1].

Name	1-(3-chlorophenyl)-2-[[1,1,1,3,3,3-hexadeuterio-2-(trideuteriomethyl)propan-2-yl]amino]propan-1-one
Synonyms	bupropion-d9 [2H9]-Bupropion propion SR

Description	Bupropion D9 is a deuterium labeled Bupropion. Bupropion is an atypical antidepressant of the aminoketone group and inhibits dopamine, norepinephrine reuptake and blocks several nicotinic receptors[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease
In Vitro	Major active metabolites of Bupropion, hydroxybupropion, threohydrobupropion, and erythrohydrobupropion reach higher plasma concentrations than bupropion[1].
References	[1]. Rafaela Costa, et al. Pharmacokinetic and Pharmacodynamic of Bupropion: Integrative Overview of Relevant Clinical and Forensic Aspects. Drug Metab Rev. 2019 Aug;51(3):293-313.