- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: 4-quinolone
- Price: ￥518.0/100g ￥158.0/25g
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: 4-Hydroxyquinoline
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 4-Hydroxyquinoline
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: 4-Hydroxyquinoline
- Price: ￥Inquiry/1kg
- Purity: 99.5%
- Stocking Period: Inquiry
- Contact: Vinnie
611-36-9
611-36-9 structure
- Name: 4-quinolone
- Chemical Name: quinolin-4-ol
- CAS Number: 611-36-9
- Molecular Formula: C9H7NO
- Molecular Weight: 145.158
- Catalog: Pharmaceutical intermediate Heterocyclic compound Quinoline compound
- Create Date: 2018-07-20 00:25:54
- Modify Date: 2024-01-02 13:14:07
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4-Quinolone (Kynurine) is a quinoline derivative. Kynurine pathway modulates tryptophan metabolism and involves in neuroprotective effect. Kynurine promotes tumor cell survival and motility by suppressing antitumor immune[1][2].
| Name | quinolin-4-ol |
|---|---|
| Synonyms |
4-Quinolinol
Chinolin-4-ol p-hydroxyquinoline 4-quinolone 4(1H)-QUINOLINONE Chinolin-4(1H)-on Quinolin-4(1H)-one quinolin-4-one 1,4-Dihydroquinoline-4-one HYDROXYQUINOLINE,4 4-hydroxyquinoline acid KYNURINE 4-Hydroxyquinoline 4-oxo-1,4-dihydroquinoline 4-hydroxy-quinolin EINECS 210-268-2 quinolin-4-ol quinoline-4-ol MFCD00006777 |
| Description | 4-Quinolone (Kynurine) is a quinoline derivative. Kynurine pathway modulates tryptophan metabolism and involves in neuroprotective effect. Kynurine promotes tumor cell survival and motility by suppressing antitumor immune[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | 4-Quinolone (Kynurine) promotes tumor cell survival and motility by suppressing antitumor immune responses through AhR in an autocrine/paracrine fashion. This system is particularly active in human brain tumors where the activation of AhR enhances the expression of TDO producing more kynurine and kynurinic acid. In the healthy human brain, very low levels of TDO exist, whereas, in human brain tumors, the TDO protein levels increase with malignancy[3]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 313.0±15.0 °C at 760 mmHg |
| Melting Point | 200-202 °C(lit.) |
| Molecular Formula | C9H7NO |
| Molecular Weight | 145.158 |
| Flash Point | 143.1±20.4 °C |
| Exact Mass | 145.052765 |
| PSA | 33.12000 |
| LogP | 2.45 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.691 |
CHEMICAL IDENTIFICATION
|
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36-S37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | VC4070000 |
| HS Code | 2933499090 |
| Precursor 9 | |
|---|---|
| DownStream 10 | |
![2-ethyl-1-(2-methylpropyl)imidazo[4,5-c]quinolin-4-amine structure](https://www.chemsrc.com/caspic/245/149876-20-0.png)
![N-[1-(2-methylpropyl)imidazo[4,5-c]quinolin-4-yl]benzamide structure](https://www.chemsrc.com/caspic/101/144660-62-8.png)
| HS Code | 2933499090 |
|---|---|
| Summary | 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |