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84-60-6

84-60-6 structure
84-60-6 structure
  • Name: 2,6-DIHYDROXY-ANTHRAQUINONE
  • Chemical Name: anthraflavic acid
  • CAS Number: 84-60-6
  • Molecular Formula: C14H8O4
  • Molecular Weight: 240.211
  • Catalog: Chemical reagent Organic reagent Aromatic ketone
  • Create Date: 2018-12-21 17:52:21
  • Modify Date: 2024-01-02 19:39:01
  • Anthraflavic acid, a flavonoid, is a potent IQ mutagenicity inhibitor by virtue of its ability to inhibit both its microsomal and cytosolic activation pathways. Anthraflavic acid is a potent and specific cytochrome P-448 inhibitor activity an enzyme system closely associated with the activation of many chemical carcinogens[1].

Name anthraflavic acid
Synonyms 2,6-DIHYDROXY-ANTHRAQUINONE
2,6-Dihydroxy-9,10-anthraquinone
EINECS 201-544-3
2,6-DIHYDROXYANTHRAQUINONE
MFCD00001228
9,10-Anthracenedione, 2,6-dihydroxy-
2,6-Dihydroxyanthracene-9,10-dione
Description Anthraflavic acid, a flavonoid, is a potent IQ mutagenicity inhibitor by virtue of its ability to inhibit both its microsomal and cytosolic activation pathways. Anthraflavic acid is a potent and specific cytochrome P-448 inhibitor activity an enzyme system closely associated with the activation of many chemical carcinogens[1].
Related Catalog
References

[1]. Ayrton AD, et al. Anthraflavic acid inhibits the mutagenicity of the food mutagen IQ: mechanism of action. Mutat Res. 1988 Mar-Apr;207(3-4):121-5.

Density 1.5±0.1 g/cm3
Boiling Point 442.1±35.0 °C at 760 mmHg
Melting Point >320 °C(lit.)
Molecular Formula C14H8O4
Molecular Weight 240.211
Flash Point 235.3±22.4 °C
Exact Mass 240.042252
PSA 74.60000
LogP 3.36
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.733
Stability Stable. Incompatible with strong oxidizing agents.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CB6675000
CHEMICAL NAME :
Anthraquinone, 2,6-dihydroxy-
CAS REGISTRY NUMBER :
84-60-6
BEILSTEIN REFERENCE NO. :
2054127
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C14-H8-O4
MOLECULAR WEIGHT :
240.22
WISWESSER LINE NOTATION :
L C666 BV IVJ DQ LQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
100 ug/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 40,203,1976
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S26-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS CB6675000
HS Code 2914690090
HS Code 2914690090
Summary 2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%