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53846-50-7

53846-50-7 structure
53846-50-7 structure
  • Name: 8-Prenylnaringenin
  • Chemical Name: 8-Prenylnaringenin
  • CAS Number: 53846-50-7
  • Molecular Formula: C20H20O5
  • Molecular Weight: 340.370
  • Catalog: Natural product Flavonoids
  • Create Date: 2016-06-08 04:21:40
  • Modify Date: 2025-08-21 09:45:11
  • 8-prenylnaringenin is a prenylflavonoid isolated from hop cones (Humulus lupulus), with cytotoxicity. 8-prenylnaringenin has anti-proliferative activity against HCT-116 colon cancer cells via induction of intrinsic and extrinsic pathway-mediated apoptosis. 8-Prenylnaringenin also promotes recovery from immobilization-induced disuse muscle atrophy through activation of the Akt phosphorylation pathway in mice[1] [2] [3].
Name 8-Prenylnaringenin
Synonyms 8-Prenylnaringenin
5,7-Dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-2,3-dihydro-4H-chromen-4-one
4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-butenyl)-
Description 8-prenylnaringenin is a prenylflavonoid isolated from hop cones (Humulus lupulus), with cytotoxicity. 8-prenylnaringenin has anti-proliferative activity against HCT-116 colon cancer cells via induction of intrinsic and extrinsic pathway-mediated apoptosis. 8-Prenylnaringenin also promotes recovery from immobilization-induced disuse muscle atrophy through activation of the Akt phosphorylation pathway in mice[1] [2] [3].
Related Catalog
References

[1]. Koosha S, et al. Antiproliferative and apoptotic activities of 8-prenylnaringenin against human colon cancer cells. Life Sci. 2019 Jul 3:116633.

[2]. Mukai R, et al. 8-Prenylnaringenin promotes recovery from immobilization-induced disuse muscle atrophy through activation of the Akt phosphorylation pathway in mice. Am J Physiol Regul Integr Comp Physiol. 2016 Dec 1;311(6):R1022-R1031.

[3]. Stompor M, et al. In Vitro Effect of 8-Prenylnaringenin and Naringenin on Fibroblasts and Glioblastoma Cells-Cellular Accumulation and Cytotoxicity. Molecules. 2017 Jun 30;22(7).
Density 1.3±0.1 g/cm3
Boiling Point 597.6±50.0 °C at 760 mmHg
Molecular Formula C20H20O5
Molecular Weight 340.370
Flash Point 216.4±23.6 °C
Exact Mass 340.131073
PSA 86.99000
LogP 5.28
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.642
Storage condition 2-8°C
Hazard Codes Xi
RIDADR NONH for all modes of transport
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