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69123-93-9

69123-93-9 structure
69123-93-9 structure
  • Name: 2'-fluoro-5-bromo-1-beta-D-arabinofuranosylcytosine
  • Chemical Name: 4-amino-5-bromo-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
  • CAS Number: 69123-93-9
  • Molecular Formula: C9H11BrFN3O4
  • Molecular Weight: 324.10
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
  • Create Date: 2017-09-27 11:12:31
  • Modify Date: 2024-01-15 13:23:45
  • 5-Bromo-2’-deoxy-2’-fluoro-beta-D-arabinocytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

Name 4-amino-5-bromo-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Synonyms 2'-Fluoro-5-bromo-aracytosine
Description 5-Bromo-2’-deoxy-2’-fluoro-beta-D-arabinocytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
Related Catalog
References

[1]. Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.  

Density 2.21 g/cm3
Boiling Point 513.3ºC at 760 mmHg
Molecular Formula C9H11BrFN3O4
Molecular Weight 324.10
Flash Point 264.3ºC
Exact Mass 338.98700
PSA 130.83000
Index of Refraction 1.741

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69123-93-9 structure

69123-93-9

Literature: Sloan Kettering Institute for Cancer Research Patent: US4211773 A1, 1980 ; Title/Abstract Full Text Show Details Sloan-Kettering Institute for Cancer Research Patent: US4594339 A1, 1986 ;
Precursor  1

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