5868-06-4

5868-06-4 structure

Name: Fentonium
Chemical Name: [8-methyl-8-[2-oxo-2-(4-phenylphenyl)ethyl]-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate,bromide
CAS Number: 5868-06-4
Molecular Formula: C₃₁H₃₄BrNO₄
Molecular Weight: 564.51000
Catalog: Research Areas Neurological Disease
Create Date: 2018-05-24 08:00:00
Modify Date: 2024-01-21 15:14:43
Fentonium bromide is an anti-ulcerogenic, anticholinergic and antispasmodic agent. Fentonium bromide can be used in the research of neurological conditions[1][2][3].

Name	[8-methyl-8-[2-oxo-2-(4-phenylphenyl)ethyl]-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate,bromide
Synonyms	Fentonio bromuro [DCIT] Ulcesium Z 326 Fentonii bromidum [INN-Latin] Bromure de fentonium [INN-French] FA 402 Ketoscilium Fentonium bromide Phentonium bromide

Description	Fentonium bromide is an anti-ulcerogenic, anticholinergic and antispasmodic agent. Fentonium bromide can be used in the research of neurological conditions[1][2][3].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
In Vivo	Fentonium bromide (1 mg/kg, i.v.) is an effective antagonist of gastric secretion in rats[1]. Fentonium bromide (phentonium, 1 mg/kg, i.p.) prevents stress ulcers in rats[1]. Animal Model: Bethanechol-, pentagastrin-, and caerulein-induced gastric secretion in rats[1] Dosage: 1 mg/kg Administration: Intravenous injection (i.v.) Result: Inhibited gastric acid secretion. Animal Model: Rats[2] Dosage: 1 mg/kg Administration: Intraperitoneal injection (i.p.) Result: Decreased both the number of pre-ulceral lesions and the number of gastroduodenal ulcers in comparison with untreated controls.