406-90-6

406-90-6 structure
406-90-6 structure
  • Name: Fluroxene
  • Chemical Name: 2-ethenoxy-1,1,1-trifluoroethane
  • CAS Number: 406-90-6
  • Molecular Formula: C4H5F3O
  • Molecular Weight: 126.07700
  • Catalog: Research Areas Neurological Disease
  • Create Date: 2018-09-15 14:56:25
  • Modify Date: 2024-01-04 10:20:40
  • Fluroxene is a volatile, inhalational anesthetic, and was the first halogenated hydrocarbon anesthetic to be introduced.

Name 2-ethenoxy-1,1,1-trifluoroethane
Synonyms FLUROXENE
Fluoromar
EINECS 206-977-1
2,2,2-trifluoroethyl vinyl ether
MFCD00864407
Description Fluroxene is a volatile, inhalational anesthetic, and was the first halogenated hydrocarbon anesthetic to be introduced.
Related Catalog
Density 1,135 g/cm3
Boiling Point 42-43°C
Molecular Formula C4H5F3O
Molecular Weight 126.07700
Flash Point -30°C
Exact Mass 126.02900
PSA 9.23000
LogP 1.70880
Vapour Pressure 96.6mmHg at 25°C
Index of Refraction 1.3192
Storage condition 2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KO4250000
CHEMICAL NAME :
Ether, 2,2,2-trifluoroethyl vinyl
CAS REGISTRY NUMBER :
406-90-6
BEILSTEIN REFERENCE NO. :
1745876
LAST UPDATED :
199701
DATA ITEMS CITED :
16
MOLECULAR FORMULA :
C4-H5-F3-O
MOLECULAR WEIGHT :
126.09
WISWESSER LINE NOTATION :
FXFF1O1U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
2 pph/90M
TOXIC EFFECTS :
Liver - jaundice, other or unclassified Liver - liver function tests impaired
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4 pph/1H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
DOSE :
8 pph/20M
SEX/DURATION :
female 22 week(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - other effects to embryo
TYPE OF TEST :
Sex chromosome loss and nondisjunction

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Rodent - hamster Ovary
REFERENCE :
ANESAV Anesthesiology. (Lippincott/Harper, Journal Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740) V.1- 1940- Volume(issue)/page/year: 50,426,1979 *** REVIEWS *** IARC Cancer Review:Animal No Adequate Data IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,93,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-DENMARK:TWA 2 ppm (10 mg/m3) JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO FLUROXENE-air:CL 2 ppm/60M REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M5153 No. of Facilities: 112 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 448 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M5153 No. of Facilities: 3 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 5 (estimated)
Hazard Codes F: Flammable;Xi: Irritant;
Risk Phrases R11
Safety Phrases S16-S36-S39-S26
RIDADR 1993
RTECS KO4250000
Packaging Group II
Hazard Class 3
HS Code 2909199090

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406-90-6 structure

406-90-6

Literature: Brey; Tarrant Journal of the American Chemical Society, 1957 , vol. 79, p. 6533,6534,6536

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406-90-6 structure

406-90-6

Literature: Tarrant,P.; Stump,E.C. Journal of Organic Chemistry, 1964 , vol. 29, p. 1198 - 1202
HS Code 2909199090
Summary 2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%