1242137-15-0
1242137-15-0 structure
- Name: Enzalutamide carboxylic acid
- Chemical Name: Enzalutamide Carboxylic acid
- CAS Number: 1242137-15-0
- Molecular Formula: C20H13F4N3O3S
- Molecular Weight: 451.39400
- Catalog: Research Areas Cancer
- Create Date: 2018-06-05 08:00:00
- Modify Date: 2024-02-01 16:00:11
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Enzalutamide carboxylic acid (MDV3100 carboxylic acid) is an inactive metabolite of Enzalutamide (MDV3100). Enzalutamide is an androgen receptor (AR) antagonist[1].
| Name | Enzalutamide Carboxylic acid |
|---|---|
| Synonyms | Enzalutamide Impurity 1 |
| Description | Enzalutamide carboxylic acid (MDV3100 carboxylic acid) is an inactive metabolite of Enzalutamide (MDV3100). Enzalutamide is an androgen receptor (AR) antagonist[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Enzalutamide is converted into its major metabolites, N-desmethyl enzalutamide and carboxylic acid enzalutamide, by cytochrome P450 (CYP) 3A4/5 and CYP2C8, respectively. N-desmethyl enzalutamide has clinically relevant anti-androgen capacities similar to enzalutamide, whereas carboxylic acid enzalutamide is inactive[1]. |
| References |
| Molecular Formula | C20H13F4N3O3S |
|---|---|
| Molecular Weight | 451.39400 |
| Exact Mass | 451.06100 |
| PSA | 116.73000 |
| LogP | 4.46108 |
| Hazard Codes | Xi |
|---|