Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Dehydroacetic acid
Price: ￥318.0/500g ￥98.0/100g
Purity: 99.0%
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Contact: Liu jia

DC Chemicals Limited
China
Product Name: Dehydroacetic Acid
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Purity: 98.0%
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Dehydroacetic acid
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Purity: 98.0%
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Zhejiang Hangyu API Co., Ltd
China
Product Name: Dehydroacetic acid
Price: ￥Inquiry/1kg
Purity: 99.5%
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Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Dehydroacetic Acid
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Purity: 99.0%
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Contact: Anson

520-45-6

520-45-6 structure

Name: Dehydroacetic acid
Chemical Name: Dehydroacetic acid
CAS Number: 520-45-6
Molecular Formula: C₈H₈O₄
Molecular Weight: 168.147
Catalog: Chemical reagent Organic reagent fatty acid
Create Date: 2018-09-09 15:47:02
Modify Date: 2024-01-02 11:50:16
Dehydroacetic acid is an organic compound, classified as a pyrone derivative and is used mostly as a fungicide and bactericide.

Name	Dehydroacetic acid
Synonyms	DEHYDRACETSAEURE DEHYDRACETIC ACID dehydro-aceticaci EINECS 212-227-4 2-Acetyl-5-hydroxy-3-oxo-4-hexenoic acid δ-lactone Geogard(R) 361 Geogard(R) 221 dhaa 3-Acetyl-6-methyl-2H-pyran-2,4(3H)-dione 2H-Pyran-2,4(3H)-dione, 3-acetyl-6-methyl- Geogard(R) 111A Dehydroacetic Acid MFCD00066709 3-acetyl-6-methyl-(2H)-pyran-2,4(3H)dione DEHYDRANONE DHA Methylacetopyronone

Description	Dehydroacetic acid is an organic compound, classified as a pyrone derivative and is used mostly as a fungicide and bactericide.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Signaling Pathways >> Anti-infection >> Fungal Research Areas >> Infection

Density	1.3±0.1 g/cm3
Boiling Point	332.6±42.0 °C at 760 mmHg
Melting Point	111-113 °C(lit.)
Molecular Formula	C₈H₈O₄
Molecular Weight	168.147
Flash Point	150.5±27.9 °C
Exact Mass	168.042252
PSA	60.44000
LogP	0.35
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.490
Stability	Stable. Incompatible with oxidizing agents, bases, reducing agents.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UP8050000

CHEMICAL NAME :: 2H-Pyran-2,4(3H)-dione, 3-acetyl-6-methyl-

CAS REGISTRY NUMBER :: 520-45-6

BEILSTEIN REFERENCE NO. :: 0006129

LAST UPDATED :: 199710

DATA ITEMS CITED :: 14

MOLECULAR FORMULA :: C8-H8-O4

MOLECULAR WEIGHT :: 168.16

WISWESSER LINE NOTATION :: T6OV DV CHJ CV1 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: WRPCA2 World Review of Pest Control. (London, UK) V.1-10, 1962-71. Discontinued. Volume(issue)/page/year: 9,119,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1330 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: SKEZAP Shokuhin Eiseigaku Zasshi. Food Hygiene Journal. (Nippon Shokuhin Eisei Gakkai c/o Shokuhin Eisei Senta, 2-6-1 Jingumae, Shibuya-ku, Tokyo 150, Japan) V.1- 1960- Volume(issue)/page/year: 12,520,1971

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1186 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 99,98,1950

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 4(3),123,1985 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2100 mg/kg/11D-I

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 99,57,1950

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 36400 mg/kg/2Y-C

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - chronic pulmonary edema Liver - changes in liver weight Nutritional and Gross Metabolic - other changes

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 99,57,1950

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Primate - monkey

DOSE/DURATION :: 3300 mg/kg/18D-I

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 99,57,1950 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 592 mg/kg/37W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

REFERENCE :: BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 20,134,1966 *** REVIEWS *** TOXICOLOGY REVIEW JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 4(3),123,1985 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1243 No. of Facilities: 28 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 1288 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1243 No. of Facilities: 83 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 925 (estimated) No. of Female Employees: 679 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Precautionary Statements	P301 + P312 + P330
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn:Harmful;
Risk Phrases	R22
Safety Phrases	S22
RIDADR	NONH for all modes of transport
WGK Germany	1
RTECS	UP8050000
Packaging Group	II; III
Hazard Class	4.1
HS Code	29322980

Precursor 9
5394-63-8 141-97-9 2911-22-0 674-82-8
108-88-3 71-43-2 1069-12-1 75-36-5
2152-34-3
DownStream 10
5093-70-9 4344-87-0 3749-51-7 504-15-4
22192-08-1 123-19-3 110-43-0 6032-29-7
3178-29-8 107-87-9

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

520-45-6	16807-48-0
4418-26-2	73939-02-3
54107-17-4	590418-48-7
114658-00-3	2432-81-7
2432-46-4	11043-91-7