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76896-80-5

76896-80-5 structure
76896-80-5 structure
  • Name: Triacsin C from Streptomyces sp.
  • Chemical Name: triacsin c
  • CAS Number: 76896-80-5
  • Molecular Formula: C11H17N3O
  • Molecular Weight: 207.272
  • Catalog: Research Areas Others
  • Create Date: 2016-08-09 12:56:27
  • Modify Date: 2025-08-25 18:59:46
  • Triacsin C (WS 1228A), a natural intracellular long-chain acyl-CoA synthetases (ACSL) inhibitor, is from Streptomyces aureofaciens. Triacsin C inhibits TAG accumulation into lipid droplets (LD) by suppressing ACSL activity[1]. Triacsin C is found to be highly effective against rotavirus replication[2].
Name triacsin c
Synonyms (3E)-1-Oxo-3-[(2E,4E,7E)-2,4,7-undecatrien-1-ylidene]triazane
2E,4E,7E-undecatriene-1-triazine
Antibiotic WS-1228A
WS 1228A
Triacsincapprox.
triacsin c from streptomyces sp.
Triacsin C
2,4,7-Undecatrienal
WS1228A
Galloflavin
2E,4E,7E-UNDECATRIENE-1-TRIAZENE
2,4,7-Undecatrienal, 2-nitrosohydrazone, (1E,2E,4E,7E)-
1-hydroxy-3-(E,E,E,-2',4',7'-undecatrienylidine)triazene
Description Triacsin C (WS 1228A), a natural intracellular long-chain acyl-CoA synthetases (ACSL) inhibitor, is from Streptomyces aureofaciens. Triacsin C inhibits TAG accumulation into lipid droplets (LD) by suppressing ACSL activity[1]. Triacsin C is found to be highly effective against rotavirus replication[2].
Related Catalog
Target

ACSL[1]

References

[1]. Dechandt CRP, et al. Triacsin C reduces lipid droplet formation and induces mitochondrial biogenesis in primary rat hepatocytes. J Bioenerg Biomembr. 2017 Oct;49(5):399-411.

[2]. Kim Y, et al. Novel triacsin C analogs as potential antivirals against rotavirus infections. Eur J Med Chem. 2012 Apr;50:311-8.
Density 0.9±0.1 g/cm3
Boiling Point 320.7±45.0 °C at 760 mmHg
Melting Point 100-102ºC
Molecular Formula C11H17N3O
Molecular Weight 207.272
Flash Point 147.7±28.7 °C
Exact Mass 207.137161
PSA 53.82000
LogP 4.02
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.485
Storage condition -20°C
RIDADR NONH for all modes of transport
WGK Germany 3
80612-69-7 structure

80612-69-7

~%

76896-80-5 structure

76896-80-5

Literature: Tanaka; Yoshida; Itoh; Imanaka Tetrahedron Letters, 1981 , vol. 22, # 35 p. 3421 - 3422
80599-06-0 structure

80599-06-0

~%

76896-80-5 structure

76896-80-5

Literature: Tanaka; Yoshida; Itoh; Imanaka Tetrahedron Letters, 1981 , vol. 22, # 35 p. 3421 - 3422
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