26046-85-5

26046-85-5 structure

Name: D-Phenothrin
Chemical Name: (3-phenoxyphenyl)methyl (1R,3R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate
CAS Number: 26046-85-5
Molecular Formula: C₂₃H₂₆O₃
Molecular Weight: 350.45100
Catalog: Chemical pesticide Insecticide Pyrethroid insecticide
Create Date: 2018-04-29 08:00:00
Modify Date: 2025-08-24 14:05:33
D-Phenothrin ((-)-trans-Phenothrin), an orally active Type II synthetic pyrethroid, is widely used to kill insects, mosquitoes, and human lice. D-Phenothrin is also used in veterinary medicine to control insect pests on animals and protect agricultural crops[1].

Name	(3-phenoxyphenyl)methyl (1R,3R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate
Synonyms	biophenothrin trans-4-Hydroxy-1-hydroxymethyl-cyclohexan EINECS 247-431-2 1-Chlor-trans,trans-dimethylcyclopropan 1r-Chlor-2t,3t-dimethyl-cyclopropan 1-Chlor-2,3-cis-dimethylcyclopropan trans-4-Hydroxycyclohexylcarbinol trans-4-Hydroxymethyl-cyclohexanol 1R-trans-Phenothrin MFCD01735786 1r-chloro-2t,3t-dimethyl-cyclopropane D-Phenothrin

Description	D-Phenothrin ((-)-trans-Phenothrin), an orally active Type II synthetic pyrethroid, is widely used to kill insects, mosquitoes, and human lice. D-Phenothrin is also used in veterinary medicine to control insect pests on animals and protect agricultural crops[1].
Related Catalog	Research Areas >> Infection
In Vivo	D-Phenothrin ((-)-trans-Phenothrin; 25-200 mg/kg; IP; 14 consecutive days) significantly, dose-dependently increases oxidative DNA damage in both organs of animals[1]. D-Phenothrin (100, 300 or 1000 mg/kg/day; p.o.; 3 days) exhibits no potential to cause adverse estrogenic or (anti-)androgenic effects[2]. Animal Model: Male Wistar albino rats (6-week-old, 150-200 g) Dosage: 25, 50, 100, 200 mg/kg Administration: IP; 14 consecutive days Result: Had a statistically significant, dose-dependent increase in oxidative DNA damage in both organs of animals.
References	[1]. Atmaca E, et al. d-Phenothrin-induced oxidative DNA damage in rat liver and kidney determined by HPLC-ECD/DAD. Environ Toxicol. 2015 May;30(5):607-13. [2]. Yamada T, et al. Lack of estrogenic or (anti-)androgenic effects of d-phenothrin in the uterotrophic and Hershberger assays. Toxicology. 2003 Apr 22;186(3):227-39.

CHEMICAL NAME :: Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, (3-phenoxyphenyl) methyl ester, (1R-trans)-

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP. Volume(issue)/page/year: (37),30,1980

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCBPBS Pesticide Biochemistry and Physiology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1971- Volume(issue)/page/year: 20,217,1983

Hazard Codes	Xi
Risk Phrases	R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Phrases	S24/25-S37/39-S26

4489-14-9

13826-35-2

26046-85-5

Literature: Magnetic Resonance in Chemistry, , vol. 31, # 1 p. 90 - 93

Precursor 2
4489-14-9 13826-35-2
DownStream 0