32663-51-7
32663-51-7 structure
- Name: cis,trans-Germacrone
- Chemical Name: 3,7-dimethyl-10-propan-2-ylidenecyclodeca-3,7-dien-1-one
- CAS Number: 32663-51-7
- Molecular Formula: C15H22O
- Molecular Weight: 218.33500
- Catalog: Signaling Pathways Apoptosis MDM-2/p53
- Create Date: 2017-01-23 21:14:27
- Modify Date: 2025-08-27 19:23:51
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cis,trans-Germacrone is a isomer of Germacrone (HY-N0440). Germacrone exhibits a wide range of antitumor, antioxidant and anti-inflammatory effects. Germacrone inhibits lung cancer cell proliferation and alters the Akt/MDM2/p53. Germacrone also arrests cell cycle at G1/S phase[1].
| Name | 3,7-dimethyl-10-propan-2-ylidenecyclodeca-3,7-dien-1-one |
|---|---|
| Synonyms | cis,trans-Germacron |
| Description | cis,trans-Germacrone is a isomer of Germacrone (HY-N0440). Germacrone exhibits a wide range of antitumor, antioxidant and anti-inflammatory effects. Germacrone inhibits lung cancer cell proliferation and alters the Akt/MDM2/p53. Germacrone also arrests cell cycle at G1/S phase[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C15H22O |
|---|---|
| Molecular Weight | 218.33500 |
| Exact Mass | 218.16700 |
| PSA | 17.07000 |
| LogP | 4.35850 |
|
~%
32663-51-7 |
| Literature: Takeda,K. et al. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1973 , p. 2212 - 2220 |
|
~3%
32663-51-7
Detail
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| Literature: Orahovats, A. S.; Bozhkova, N. V.; Hilpert, H. Tetrahedron Letters, 1983 , vol. 24, # 9 p. 947 - 950 |
| Precursor 1 | |
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| DownStream 0 | |