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2640109-28-8

2640109-28-8 structure

2640109-28-8 structure

Name: M1/M2/M4 muscarinic agonist 3
Chemical Name: M1/M2/M4 muscarinic agonist 3
CAS Number: 2640109-28-8
Molecular Formula: C₂₃H₃₁FN₂O₃
Molecular Weight: 402.50
Catalog: Signaling Pathways GPCR/G Protein mAChR
Create Date: 2024-03-19 19:21:28
Modify Date: 2024-03-19 19:21:28
M1/M2/M4 muscarinic agonist 3 (compound 45) is a muscarinic mAChR M1/M2/M4 agonist with EC50s of 3.2 nM, 32 nM and 1.7 nM, respectively[1].

Name	M1/M2/M4 muscarinic agonist 3

Description	M1/M2/M4 muscarinic agonist 3 (compound 45) is a muscarinic mAChR M1/M2/M4 agonist with EC50s of 3.2 nM, 32 nM and 1.7 nM, respectively[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> mAChR Signaling Pathways >> GPCR/G Protein >> mAChR Research Areas >> Neurological Disease
Target	EC50: 3.2 nM (M1 muscarinic receptor), 32 nM (M2 muscarinic receptor), 1.7 nM (M4 muscarinic receptor)[1]
References	[1]. Thomson C G et al. Transaminases Provide Key Chiral Building Blocks for the Synthesis of Selective M1/M4 Agonists[J]. ACS Medicinal Chemistry Letters, 2023.

Molecular Formula	C₂₃H₃₁FN₂O₃
Molecular Weight	402.50

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