2640109-42-6

2640109-42-6 structure

Name: M1/M2/M4 muscarinic agonist 1
Chemical Name: M1/M2/M4 muscarinic agonist 1
CAS Number: 2640109-42-6
Molecular Formula: C₂₄H₃₄N₂O₃
Molecular Weight: 398.54
Catalog: Signaling Pathways GPCR/G Protein mAChR
Create Date: 2024-01-30 20:47:34
Modify Date: 2024-01-30 20:47:34
M1/M2/M4 muscarinic agonist 1 (Compound 42) is a muscarinic M4/M1/M2 agonist with EC50 values of 6.5, 26 and 210 nM for M4/M1/M2, respectively. M1/M2/M4 muscarinic agonist 1 can be used for research on mental diseases, such as schizophrenia, delusion, etc[1].

Name	M1/M2/M4 muscarinic agonist 1

Description	M1/M2/M4 muscarinic agonist 1 (Compound 42) is a muscarinic M4/M1/M2 agonist with EC50 values of 6.5, 26 and 210 nM for M4/M1/M2, respectively. M1/M2/M4 muscarinic agonist 1 can be used for research on mental diseases, such as schizophrenia, delusion, etc[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> mAChR Signaling Pathways >> GPCR/G Protein >> mAChR Research Areas >> Neurological Disease
Target	mAChR1:26 nM (EC50) mAChR2:210 nM (EC50) mAChR4:6.5 nM (EC50)
References	[1]. Christopher G Thomson, et al. Transaminases Provide Key Chiral Building Blocks for the Synthesis of Selective M1/M4 Agonists. ACS Med. Chem. Lett. 2023. Nov 6.

Molecular Formula	C₂₄H₃₄N₂O₃
Molecular Weight	398.54