4669-23-2
4669-23-2 structure
- Name: Triethylene glycol monodecyl ether
- Chemical Name: 2-[2-(2-decoxyethoxy)ethoxy]ethanol
- CAS Number: 4669-23-2
- Molecular Formula: C16H34O4
- Molecular Weight: 290.43900
- Catalog: Catalysts and additives Polyethylene glycol derivative
- Create Date: 2018-07-30 21:34:15
- Modify Date: 2025-08-25 14:10:47
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Triethylene glycol monodecyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 2-[2-(2-decoxyethoxy)ethoxy]ethanol |
|---|---|
| Synonyms |
Decyltriglycol
Triethylene glycol monodecyl ether triethylene glycol monodecyl ether Emulgin BL 309 C10E3 3,6,9-trioxa-1-nonadecanol n-decyl triethylene glycol monoether Triethyleneglycol monodecyl ether solution triethylene glycol mono-n-decyl ether Decyl triethylene glycol ether Triethyleneglycol monodecyl ether 1 mM solution |
| Description | Triethylene glycol monodecyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 0.936 g/mL at 20ºC(lit.) |
|---|---|
| Molecular Formula | C16H34O4 |
| Molecular Weight | 290.43900 |
| Exact Mass | 290.24600 |
| PSA | 47.92000 |
| LogP | 3.16920 |
| Index of Refraction | n20/D 1.449 |
| Storage condition | 2-8°C |
| Personal Protective Equipment | Eyeshields;Gloves |
|---|---|
| Safety Phrases | 24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
|
~84%
4669-23-2 |
| Literature: Dow Global Technologies LLC; TULCHINSKY, Michael, L.; BRIGGS, John, R.; RAND, Cynthia, L. Patent: EP2318346 B1, 2013 ; Location in patent: Paragraph 0077 ; |
|
~%
4669-23-2 |
| Literature: Kim, Ki-Hyun; Kim, Jong-Uk; Cha, Sang-Ho; Lee, Jong-Chan Journal of the American Chemical Society, 2009 , vol. 131, p. 7482 - 7483 |
| Precursor 3 | |
|---|---|
| DownStream 2 | |
![1-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]decane structure](https://image.chemsrc.com/caspic/056/132364-54-6.png)
![3,4-bis[2-[2-(2-decoxyethoxy)ethoxy]ethoxy]benzaldehyde structure](https://image.chemsrc.com/caspic/063/656821-30-6.png)