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4669-23-2

4669-23-2 structure

Name: Triethylene glycol monodecyl ether
Chemical Name: 2-[2-(2-decoxyethoxy)ethoxy]ethanol
CAS Number: 4669-23-2
Molecular Formula: C₁₆H₃₄O₄
Molecular Weight: 290.43900
Catalog: Catalysts and additives Polyethylene glycol derivative
Create Date: 2018-07-30 21:34:15
Modify Date: 2024-01-16 13:06:31
Triethylene glycol monodecyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2-[2-(2-decoxyethoxy)ethoxy]ethanol
Synonyms	Decyltriglycol Triethylene glycol monodecyl ether triethylene glycol monodecyl ether Emulgin BL 309 C10E3 3,6,9-trioxa-1-nonadecanol n-decyl triethylene glycol monoether Triethyleneglycol monodecyl ether solution triethylene glycol mono-n-decyl ether Decyl triethylene glycol ether Triethyleneglycol monodecyl ether 1 mM solution

Description	Triethylene glycol monodecyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

Density	0.936 g/mL at 20ºC(lit.)
Molecular Formula	C₁₆H₃₄O₄
Molecular Weight	290.43900
Exact Mass	290.24600
PSA	47.92000
LogP	3.16920
Index of Refraction	n20/D 1.449
Storage condition	2-8°C

Personal Protective Equipment	Eyeshields;Gloves
Safety Phrases	24/25
RIDADR	NONH for all modes of transport
WGK Germany	3

112-31-2

112-27-6

~84%

112-30-1

4669-23-2

Literature: Dow Global Technologies LLC; TULCHINSKY, Michael, L.; BRIGGS, John, R.; RAND, Cynthia, L. Patent: EP2318346 B1, 2013 ; Location in patent: Paragraph 0077 ;

112-29-8

112-27-6

4669-23-2

Literature: Kim, Ki-Hyun; Kim, Jong-Uk; Cha, Sang-Ho; Lee, Jong-Chan Journal of the American Chemical Society, 2009 , vol. 131, p. 7482 - 7483

Precursor 3
112-31-2 112-27-6 112-29-8
DownStream 2
132364-54-6 656821-30-6

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