1391499-52-7

1391499-52-7 structure

Name: 5-HT2A receptor agonist-3
Chemical Name: 5-HT2A receptor agonist-3
CAS Number: 1391499-52-7
Molecular Formula: C₂₁H₂₆BrNO₃
Molecular Weight: 420.34
Catalog: Signaling Pathways GPCR/G Protein 5-HT Receptor
Create Date: 2024-09-18 11:24:17
Modify Date: 2025-08-25 07:20:20
5-HT2A receptor agonist-3 is the most selective agonist for the human 5-HT2A receptor yet discovered, with a Ki of 2.5 nM, and with 124-fold selectivity for 5-HT2A over the structurally similar 5-HT2C receptor[1].

Name	5-HT2A receptor agonist-3

Description	5-HT2A receptor agonist-3 is the most selective agonist for the human 5-HT2A receptor yet discovered, with a Ki of 2.5 nM, and with 124-fold selectivity for 5-HT2A over the structurally similar 5-HT2C receptor[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
Target	2.5 nM (human 5-HT2A)
References	[1]. Juncosa JI Jr, et al. Extensive rigid analogue design maps the binding conformation of potent N-benzylphenethylamine 5-HT2A serotonin receptor agonist ligands. ACS Chem Neurosci. 2013;4(1):96-109.

Molecular Formula	C₂₁H₂₆BrNO₃
Molecular Weight	420.34