1374648-47-1
1374648-47-1 structure
- Name: Nsc-670224
- Chemical Name: NSC-670224
- CAS Number: 1374648-47-1
- Molecular Formula: C21H34Cl3NO
- Molecular Weight: 422.86
- Catalog: Research Areas Others
- Create Date: 2024-09-07 17:26:47
- Modify Date: 2024-09-07 17:26:47
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NSC-670224 is an inhibitor of histone deacetylases-6 (HDAC6) and nuclear factor-κB (NF-κB) activation blocker. It has been shown to be toxic to Saccharomyces cerevisiae at low micromolar concentrations, potentially acts via a mechanism of action related to that of tamoxifen.
| Name | NSC-670224 |
|---|
| Description | NSC-670224 is an inhibitor of histone deacetylases-6 (HDAC6) and nuclear factor-κB (NF-κB) activation blocker. It has been shown to be toxic to Saccharomyces cerevisiae at low micromolar concentrations, potentially acts via a mechanism of action related to that of tamoxifen. |
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| References | 1. Zuckerman NB, Myers AS, Quan TK, Bray WM, Lokey RS, Hartzog GA, Konopelski JP. Structural determination of NSC 670224, synthesis of analogues and biological evaluation. ChemMedChem. 2012 May;7(5):761-5. doi: 10.1002/cmdc.201200038. Epub 2012 Feb 29. PubMed PMID: 22378491; PubMed Central PMCID: PMC3516922. |
| Molecular Formula | C21H34Cl3NO |
|---|---|
| Molecular Weight | 422.86 |