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20150-34-9

20150-34-9 structure
20150-34-9 structure
  • Name: Ferrous bisglycinate
  • Chemical Name: Ferrous Bisglycinate Food Grade
  • CAS Number: 20150-34-9
  • Molecular Formula: C4H8FeN2O4
  • Molecular Weight: 203.962
  • Catalog: Biochemical Common amino acids and protein drugs
  • Create Date: 2018-02-07 08:00:00
  • Modify Date: 2024-01-05 09:34:43
  • Ferrous bisglycinate is an orally active iron fortificants and therapeutic iron supplements. Ferrous bisglycinate can be used for the research of iron deficiency anemia[1][2].
Name Ferrous Bisglycinate Food Grade
Synonyms Iron protochloride
Natural lawrencite
Ferro 66
ferrous bisglycinate
ferrous glycinate
FERROUS CHLORIDE
FeCl2
iron dichloride
ferrous dichloride
Description Ferrous bisglycinate is an orally active iron fortificants and therapeutic iron supplements. Ferrous bisglycinate can be used for the research of iron deficiency anemia[1][2].
Related Catalog
In Vitro Ferrous bisglycinate (25-200 μM; 2 h) does not affect the Caco-2 cells viability[2]. Ferrous bisglycinate (25 μM; 2 h) increases ferritin content in the Caco-2 cells[2]. Cell Viability Assay[2] Cell Line: Caco-2 cells Concentration: 0, 25, 50, 100, 200 μM Incubation Time: 2 hours Result: Did not affect the viability of wild-type and divalent metal transporter 1 (DMT1) knockout Caco-2 cells. Western Blot Analysis[2] Cell Line: Caco-2 cells Concentration: 25 μM Incubation Time: 2 hours Result: Increased ferritin content and decreased DMT1 expression levels significantly in the wild-type cells.
In Vivo Ferrous bisglycinate (500 mg/kg iron; p.o.) exerts a protective effect on colitis in mice[3]. Animal Model: Female C57BL/6 mice are induced colitis by dextran sodium sulfate (DSS)[3] Dosage: 500 mg/kg iron Administration: P.o. (add to the diet) for 10 days Result: Had the best survival rates (100%). Caused the least body lost (9% body loss).
References

[1]. Ferrari P, et, al. Treatment of mild non-chemotherapy-induced iron deficiency anemia in cancer patients: comparison between oral ferrous bisglycinate chelate and ferrous sulfate. Biomed Pharmacother. 2012 Sep; 66(6): 414-8.

[2]. Yu X, et, al. Iron Transport from Ferrous Bisglycinate and Ferrous Sulfate in DMT1-Knockout Human Intestinal Caco-2 Cells. Nutrients. 2019 Feb 26; 11(3): 485.

[3]. Constante M, et, al. Iron Supplements Modulate Colon Microbiota Composition and Potentiate the Protective Effects of Probiotics in Dextran Sodium Sulfate-induced Colitis. Inflamm Bowel Dis. 2017 May; 23(5): 753-766.
Boiling Point 240.9ºC at 760 mmHg
Molecular Formula C4H8FeN2O4
Molecular Weight 203.962
Exact Mass 203.983353
PSA 132.30000
Hazard Codes Xi
Precursor  2

DownStream  1


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title: CAS No. 20150-34-9 | Chemsrc address: https://www.chemsrc.com/en/baike/178070.html

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