2944462-67-1

2944462-67-1 structure

Name: Tubulin inhibitor 33
Chemical Name: Tubulin inhibitor 33
CAS Number: 2944462-67-1
Molecular Formula: C₂₄H₂₂N₄O₃
Molecular Weight: 414.46
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2023-10-29 07:49:52
Modify Date: 2024-01-24 02:11:55
Tubulin inhibitor 33, a tubulin polymerization inhibitor, inhibits tubulin polymerization in a dose-dependent manner with an IC50 of 9.05 μM. Tubulin inhibitor 33 has antitumor effects and induces cell apoptosis that can be used for antitumor research[1].

Name	Tubulin inhibitor 33

Description	Tubulin inhibitor 33, a tubulin polymerization inhibitor, inhibits tubulin polymerization in a dose-dependent manner with an IC50 of 9.05 μM. Tubulin inhibitor 33 has antitumor effects and induces cell apoptosis that can be used for antitumor research[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
Target	IC50: 9.05 μM (tubulin)[1]
References	[1]. Ren Y, et.al. X-ray Crystal Structure-Guided Discovery of Novel Indole Analogues as Colchicine-Binding Site Tubulin Inhibitors with Immune-Potentiating and Antitumor Effects against Melanoma. J Med Chem. 2023 May 25;66(10):6697-6714.

Molecular Formula	C₂₄H₂₂N₄O₃
Molecular Weight	414.46