2446880-46-0
2446880-46-0 structure
- Name: ND-011992
- Chemical Name: ND-011992
- CAS Number: 2446880-46-0
- Molecular Formula: C21H14F3N3O
- Molecular Weight: 381.35
- Catalog: Signaling Pathways Anti-infection Bacterial
- Create Date: 2023-10-23 17:19:23
- Modify Date: 2024-01-02 23:22:31
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ND-011992 is a reversible, selective quinazoline-type inhibitor targeting quinone reductases and quinol oxidases. ND-011992 inhibits respiratory complex I and bo3 oxidase in addition to bd-I and bd-II oxidases in E. coli strain BL21*Δcyo with the IC50 of 0.12, 2.47, 0.63 and 1.3 μM, respectively. ND-011992 can be used for tuberculosis study[1].
| Name | ND-011992 |
|---|
| Description | ND-011992 is a reversible, selective quinazoline-type inhibitor targeting quinone reductases and quinol oxidases. ND-011992 inhibits respiratory complex I and bo3 oxidase in addition to bd-I and bd-II oxidases in E. coli strain BL21*Δcyo with the IC50 of 0.12, 2.47, 0.63 and 1.3 μM, respectively. ND-011992 can be used for tuberculosis study[1]. |
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| Related Catalog | |
| Target |
0.12 μM (respiratory complex I), 2.47 (bo3 oxidase), 0.63 (bd-I oxidases), 1.3 (bd-II oxidases) |
| References |
| Molecular Formula | C21H14F3N3O |
|---|---|
| Molecular Weight | 381.35 |