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864082-48-4

864082-48-4 structure
864082-48-4 structure
  • Name: Gsk466317a
  • Chemical Name: GSK466317A
  • CAS Number: 864082-48-4
  • Molecular Formula: C21H16ClF3N4O2
  • Molecular Weight: 448.83
  • Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK PKA
  • Create Date: 2023-09-26 13:02:57
  • Modify Date: 2024-01-16 11:39:22
  • GSK466317A is a PKA inhibitor, with an IC50 of 12.59 μM. GSK466317A also inhibits GRK1, GRK2, and GRK5, with IC50s of 1000, 31.62, and 39.81 μM, respectively[1].

Name GSK466317A
Description GSK466317A is a PKA inhibitor, with an IC50 of 12.59 μM. GSK466317A also inhibits GRK1, GRK2, and GRK5, with IC50s of 1000, 31.62, and 39.81 μM, respectively[1].
Related Catalog
Target

PKA:12.59 μM (IC50)

References

[1]. Homan KT, et, al. Identification and structure-function analysis of subfamily selective G protein-coupled receptor kinase inhibitors. ACS Chem Biol. 2015 Jan 16;10(1):310-9.  

Molecular Formula C21H16ClF3N4O2
Molecular Weight 448.83