2417298-29-2

2417298-29-2 structure

Name: FC-116
Chemical Name: FC-116
CAS Number: 2417298-29-2
Molecular Formula: C₂₁H₂₀FNO₄
Molecular Weight: 369.39
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2023-10-20 16:34:03
Modify Date: 2024-01-20 17:36:30
FC-11 is a Tubulin inhibitor that effectively inhibits tumor growth in mice. FC-11 can also induce endoplasmic reticulum (ER) stress to generate excess reactive oxygen species (ROS), leading to mitochondrial damage, thereby promoting apoptosis in colorectal cancer (CRC) cells by targeting microtubules. FC-11 can be used in cancer research[1].

Name	FC-116

Description	FC-11 is a Tubulin inhibitor that effectively inhibits tumor growth in mice. FC-11 can also induce endoplasmic reticulum (ER) stress to generate excess reactive oxygen species (ROS), leading to mitochondrial damage, thereby promoting apoptosis in colorectal cancer (CRC) cells by targeting microtubules. FC-11 can be used in cancer research[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
References	[1]. Liu X, et al. Fluoroindole chalcone analogues targeting the colchicine binding site of tubulin for colorectal oncotherapy. Eur J Med Chem. 2023 Sep 5;257:115540.

Molecular Formula	C₂₁H₂₀FNO₄
Molecular Weight	369.39