FC-116

Modify Date: 2025-08-25 09:49:50

FC-116 Structure
FC-116 structure
Common Name FC-116
CAS Number 2417298-29-2 Molecular Weight 369.39
Density N/A Boiling Point N/A
Molecular Formula C21H20FNO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FC-116


FC-11 is a Tubulin inhibitor that effectively inhibits tumor growth in mice. FC-11 can also induce endoplasmic reticulum (ER) stress to generate excess reactive oxygen species (ROS), leading to mitochondrial damage, thereby promoting apoptosis in colorectal cancer (CRC) cells by targeting microtubules. FC-11 can be used in cancer research[1].

 Names

Name FC-116

 FC-116 Biological Activity

Description FC-11 is a Tubulin inhibitor that effectively inhibits tumor growth in mice. FC-11 can also induce endoplasmic reticulum (ER) stress to generate excess reactive oxygen species (ROS), leading to mitochondrial damage, thereby promoting apoptosis in colorectal cancer (CRC) cells by targeting microtubules. FC-11 can be used in cancer research[1].
Related Catalog
References

[1]. Liu X, et al. Fluoroindole chalcone analogues targeting the colchicine binding site of tubulin for colorectal oncotherapy. Eur J Med Chem. 2023 Sep 5;257:115540.  

 Chemical & Physical Properties

Molecular Formula C21H20FNO4
Molecular Weight 369.39
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