2305416-07-1

2305416-07-1 structure

Name: N2-[(N,N-Dimethyl amino]methylene-N1-methyl-2’-O-methylguanosine
Chemical Name: N2-[(N,N-Dimethyl amino]methylene-N1-methyl-2’-O-methylguanosine
CAS Number: 2305416-07-1
Molecular Formula: C₁₅H₂₂N₆O₅
Molecular Weight: 366.37
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2023-06-15 16:16:28
Modify Date: 2024-04-03 16:21:36
N2-[(N,N-Dimethyl amino]methylene-N1-methyl-2’-O-methylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

Name	N2-[(N,N-Dimethyl amino]methylene-N1-methyl-2’-O-methylguanosine

Description	N2-[(N,N-Dimethyl amino]methylene-N1-methyl-2’-O-methylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. [2]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.

Molecular Formula	C₁₅H₂₂N₆O₅
Molecular Weight	366.37