2780364-50-1

2780364-50-1 structure
2780364-50-1 structure
  • Name: IL-1β-IN-1
  • Chemical Name: IL-1β-IN-1
  • CAS Number: 2780364-50-1
  • Molecular Formula: C22H34O2
  • Molecular Weight: 330.50
  • Catalog: Signaling Pathways Immunology/Inflammation Interleukin Related
  • Create Date: 2023-07-24 04:37:28
  • Modify Date: 2024-04-07 14:42:32
  • IL-1β-IN-1, cannabidiol derivative, is a potent IL-1β inhibitor. IL-1β-IN-1 has anti-inflammatory and pain-resolving properties[1].

Name IL-1β-IN-1
Description IL-1β-IN-1, cannabidiol derivative, is a potent IL-1β inhibitor. IL-1β-IN-1 has anti-inflammatory and pain-resolving properties[1].
Related Catalog
Target

IL-1β

In Vivo IL-1β-IN-1 (compound 2; 10 and 25 mg/kg; i.p.; 雌性 Sabra 小鼠) 以剂量依赖性方式改善肿胀和痛感[1]。 Animal Model: female Sabra mice, 7-8 weeks old[1] Dosage: 10 and 25 mg/kg Administration: intraperitoneal injection Result: Reduced swelling and pain sensation. Reduced plasma TNFα and IL-1β.
References

[1]. Lavi Y, et, al. Novel Synthesis of C-Methylated Phytocannabinoids Bearing Anti-inflammatory Properties. J Med Chem. 2023 Apr 27;66(8):5536-5549.  

Molecular Formula C22H34O2
Molecular Weight 330.50
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