2245842-16-2
2245842-16-2 structure
- Name: 2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite
- Chemical Name: 2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite
- CAS Number: 2245842-16-2
- Molecular Formula: C40H46FN6O7P
- Molecular Weight: 772.80
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
- Create Date: 2023-07-05 16:26:27
- Modify Date: 2024-01-28 10:59:53
-
2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia[1][2].
| Name | 2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite |
|---|
| Description | 2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia[1][2]. |
|---|---|
| Related Catalog | |
| References |
| Molecular Formula | C40H46FN6O7P |
|---|---|
| Molecular Weight | 772.80 |