105017-39-8

105017-39-8 structure

Name: (R,R)-Reboxetine mesylate
Chemical Name: (R,R)-Reboxetine mesylate
CAS Number: 105017-39-8
Molecular Formula: C₂₀H₂₇NO₆S
Molecular Weight: 409.50
Catalog: Signaling Pathways GPCR/G Protein Adrenergic Receptor
Create Date: 2023-06-15 16:28:25
Modify Date: 2025-08-25 19:56:18
(R,R)-Reboxetine mesylate is an antidepressant agent with great bioavailability. (R,R)-Reboxetine is the enantiomer of Reboxetine, which is a selective noradrenaline reuptake inhibitor. Reboxetine consists of (R,R) and (S,S) enantiomer, has low affinity for alpha-adrenergic and muscarinic receptors and low toxicity in animals[1][2].

Name	(R,R)-Reboxetine mesylate

Description	(R,R)-Reboxetine mesylate is an antidepressant agent with great bioavailability. (R,R)-Reboxetine is the enantiomer of Reboxetine, which is a selective noradrenaline reuptake inhibitor. Reboxetine consists of (R,R) and (S,S) enantiomer, has low affinity for alpha-adrenergic and muscarinic receptors and low toxicity in animals[1][2].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> mAChR Signaling Pathways >> GPCR/G Protein >> mAChR Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Neurological Disease
Target	α adrenergic receptor Muscarinic Receptors
References	[1]. Wienkers LC, et al. Cytochrome P-450-mediated metabolism of the individual enantiomers of the antidepressant agent reboxetine in human liver microsomes. Drug Metab Dispos. 1999 Nov;27(11):1334-40. [2]. Dostert P, et al. Review of the pharmacokinetics and metabolism of reboxetine, a selective noradrenaline reuptake inhibitor. Eur Neuropsychopharmacol. 1997 Apr;7 Suppl 1:S23-35; discussion S71-3.

Molecular Formula	C₂₀H₂₇NO₆S
Molecular Weight	409.50