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2299252-72-3

2299252-72-3 structure
2299252-72-3 structure
  • Name: Izumerogant
  • Chemical Name: Izumerogant
  • CAS Number: 2299252-72-3
  • Molecular Formula: C22H18ClF4N5O2
  • Molecular Weight: 495.86
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease ROR
  • Create Date: 2023-04-03 11:38:39
  • Modify Date: 2024-04-06 17:56:48
  • Izumerogant is an inverse agonist of retinoid-related orphan receptor-gamma (RORγ). Izumerogant (compound 123) also potently inhibits IL-17A, IL-17F and IFN-γ activity with IC50s <50 nM[1][2].
Name Izumerogant
Description Izumerogant is an inverse agonist of retinoid-related orphan receptor-gamma (RORγ). Izumerogant (compound 123) also potently inhibits IL-17A, IL-17F and IFN-γ activity with IC50s <50 nM[1][2].
Related Catalog
References

[1]. F Jakob, et al. Isoxazole-pyrazole derivatives and related compounds as IL-17 and IFN-γ inhibitors for treating autoimmune diseases and chronic inflammation: World Intellectual Property Organization, WO2019048541. 2019-03-14.

[2]. WHO Drug Information-World Health Organization (WHO).

Molecular Formula C22H18ClF4N5O2
Molecular Weight 495.86

Chemsrc provides CAS#:2299252-72-3 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 2299252-72-3 | Chemsrc address: https://www.chemsrc.com/en/baike/1734156.html

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