2254483-95-7
2254483-95-7 structure
- Name: Malacidin A
- Chemical Name: Malacidin A
- CAS Number: 2254483-95-7
- Molecular Formula: C56H88N12O20
- Molecular Weight: 1249.37
- Catalog: Signaling Pathways Anti-infection Bacterial
- Create Date: 2022-11-27 11:41:50
- Modify Date: 2024-10-06 11:18:38
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Malacidin A is the calcium-dependent antibiotic (CDAs). Malacidin A is highly active against many antibiotic-resistant pathogens, particularly Gram-positive bacteria[1][2].
| Name | Malacidin A |
|---|
| Description | Malacidin A is the calcium-dependent antibiotic (CDAs). Malacidin A is highly active against many antibiotic-resistant pathogens, particularly Gram-positive bacteria[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | Malacidin A has antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) in a calcium-dependent manner[1]. Malacidin A (100-250 µg/mL) has broadly active against Gram-positive bacteria including multidrug-resistant pathogens and bacteria resistant to mechanistically diverse, clinically used antibiotics with MIC values of 0.1-2.0 µg/mL[1]. |
| In Vivo | Malacidin A (4 mg/kg; apply over the wound) has antibacterial activity and inhibits bacterial load in cutaneous wound infection mice[1]. Animal Model: Male Sprague Dawley rats (8 weeks old) with cutaneous wound infection model[1] Dosage: 4 mg/kg Administration: Apply over the wound Result: Had no observed bacterial burdens in the wounds. |
| Molecular Formula | C56H88N12O20 |
|---|---|
| Molecular Weight | 1249.37 |