1803952-77-3

1803952-77-3 structure

1803952-77-3 structure

Name: BACE1-IN-11
Chemical Name: BACE1-IN-11
CAS Number: 1803952-77-3
Molecular Formula: C₃₀H₅₁N₅O₈S
Molecular Weight: 641.82
Catalog: Signaling Pathways Neuronal Signaling Beta-secretase
Create Date: 2022-10-16 19:53:55
Modify Date: 2024-01-17 12:16:52
BACE1-IN-11 is a BACE1 inhibitor. BACE1-IN-11 has the BACE1 inhibitory activity with an IC50 value of 72 μM. BACE1-IN-11 can be used for the research of Alzheimer’s disease (AD) [1].

Name	BACE1-IN-11

Description	BACE1-IN-11 is a BACE1 inhibitor. BACE1-IN-11 has the BACE1 inhibitory activity with an IC50 value of 72 μM. BACE1-IN-11 can be used for the research of Alzheimer’s disease (AD) [1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Beta-secretase Research Areas >> Neurological Disease
Target	BACE1:72 μM (IC50)
In Vitro	BACE1-IN-11(compound 1) has the BACE1 inhibitory activity with an IC50 value of 72 μM[1].
References	[1]. Takuya Otani, et al. Macrocyclic BACE1 inhibitors with hydrophobic cross-linked structures: Optimization of ring size and ring structure. Bioorg Med Chem. 2021 Dec 15;52:116517.

Molecular Formula	C₃₀H₅₁N₅O₈S
Molecular Weight	641.82