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2070009-29-7

2070009-29-7 structure
2070009-29-7 structure
  • Name: naltrexone-d4
  • Chemical Name: naltrexone-d4
  • CAS Number: 2070009-29-7
  • Molecular Formula: C20H19D4NO4
  • Molecular Weight: 345.43
  • Catalog: Signaling Pathways GPCR/G Protein Opioid Receptor
  • Create Date: 2022-11-21 16:38:37
  • Modify Date: 2024-01-13 20:40:56
  • Naltrexone-d4 is deuterium labeled Naltrexone.
Name naltrexone-d4
Description Naltrexone-d4 is deuterium labeled Naltrexone.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.  

[2]. Lobmaier PP, et al. Naltrexone depot formulations for opioid and alcohol dependence: a systematic review. CNS Neurosci Ther. 2011 Dec;17(6):629-36.  

[3]. Mannelli P, Peindl KS, Wu LT. Pharmacological enhancement of naltrexone treatment for opioid dependence: a review. Subst Abuse Rehabil. 2011 Jun;2011(2):113-123.  

[4]. Swift R, Oslin DW, Alexander M, Forman R. Adherence monitoring in naltrexone pharmacotherapy trials: a systematic review. J Stud Alcohol Drugs. 2011 Nov;72(6):1012-8.  

[5]. Makowski CT, Gwinn KM, Hurren KM. Naltrexone/bupropion: an investigational combination for weight loss and maintenance. Obes Facts. 2011;4(6):489-94.  

[6]. Hulse GK. Improving Clinical Outcomes for Naltrexone as a Management of Problem Alcohol Use. Br J Clin Pharmacol. 2012 Sep 5. doi: 10.1111/j.1365-2125.2012.04452.x.  

[7]. Naltrexone

Molecular Formula C20H19D4NO4
Molecular Weight 345.43

Chemsrc provides CAS#:2070009-29-7 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 2070009-29-7 | Chemsrc address: https://www.chemsrc.com/en/baike/1717843.html

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