893633-37-9
893633-37-9 structure
- Name: PROTAC BRD9-binding moiety 5
- Chemical Name: PROTAC BRD9-binding moiety 5
- CAS Number: 893633-37-9
- Molecular Formula: C19H18N6O
- Molecular Weight: 346.39
- Catalog: Signaling Pathways Epigenetics Epigenetic Reader Domain
- Create Date: 2022-09-12 12:15:57
- Modify Date: 2023-01-21 12:27:18
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PROTAC BRD9-binding moiety 5 is a selective BRD9 binder with an IC50 value of 4.20 μM, can be used for the synthesis of PROTACs. PROTAC BRD9-binding moiety 5 has antiproliferative activity against cancer cells[1].
| Name | PROTAC BRD9-binding moiety 5 |
|---|
| Description | PROTAC BRD9-binding moiety 5 is a selective BRD9 binder with an IC50 value of 4.20 μM, can be used for the synthesis of PROTACs. PROTAC BRD9-binding moiety 5 has antiproliferative activity against cancer cells[1]. |
|---|---|
| Related Catalog | |
| Target |
BRD9:4.2 μM (IC50) |
| In Vitro | PROTAC BRD9-binding moiety 5 (compound 7) (0-250 μM; 48h) has antiproliferative activity against Jurkat, MDA-MB-231, A375 and HCT-116[1]. Cell Proliferation Assay[1] Cell Line: Jurkat, MDA-MB-231, A375 and HCT-116 Concentration: 0-250 μM Incubation Time: 48h Result: Exhibited antiproliferative activity against Jurkat, MDA-MB-231, A375 and HCT-116 with IC50s of 77 ± 7 μM, 125 ± 8 μM, 133 ± 5 μM and 145 ± 3 μM. |
| References |
| Molecular Formula | C19H18N6O |
|---|---|
| Molecular Weight | 346.39 |