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1980064-35-4

1980064-35-4 structure

1980064-35-4 structure

Name: Bleformin A
Chemical Name: Bleformin A
CAS Number: 1980064-35-4
Molecular Formula: C₂₃H₂₀O₅
Molecular Weight: 376.40
Catalog: Signaling Pathways Neuronal Signaling AChE
Create Date: 2022-10-08 16:11:06
Modify Date: 2024-01-13 00:36:10
Bleformin A is a potent BChE inhibitor with an IC50 value of 5.2 μM. Bleformin A is a nature product that could be isolated from Bletilla striata. Bleformin A can be used for research of Alzheimer's disease (AD)[1].

Name	Bleformin A

Description	Bleformin A is a potent BChE inhibitor with an IC50 value of 5.2 μM. Bleformin A is a nature product that could be isolated from Bletilla striata. Bleformin A can be used for research of Alzheimer's disease (AD)[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
In Vitro	Bleformin A (compound 8; 0-8.302 μM) inhibits BChE with a Ki value of 4.7 μM. Bleformin A decreases Vmax and increases Km in a dose-dependent manner[1].
References	[1]. Liu Y, et, al. Biological evaluation, molecular modeling and dynamics simulation of phenanthrenes isolated from Bletilla striata as butyrylcholinesterase inhibitors. Sci Rep. 2022 Aug 11;12(1):13649.

Molecular Formula	C₂₃H₂₀O₅
Molecular Weight	376.40

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