2279945-76-3
2279945-76-3 structure
- Name: Glucocerebrosidase-IN-1
- Chemical Name: Glucocerebrosidase-IN-1
- CAS Number: 2279945-76-3
- Molecular Formula: C13H27NO3
- Molecular Weight: 245.36
- Catalog: Research Areas Metabolic Disease
- Create Date: 2022-08-17 18:56:39
- Modify Date: 2024-04-03 18:09:16
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Glucocerebrosidase-IN-1 (compound 11a) is a potent and selective GCase (glucocerebrosidase) inhibitor, with an IC50 of 29.3 μM and a Ki of 18.5 μM. Glucocerebrosidase-IN-1 can be used for the research of Gaucher disease (GD) and Parkinson’s disease (PD)[1].
| Name | Glucocerebrosidase-IN-1 |
|---|
| Description | Glucocerebrosidase-IN-1 (compound 11a) is a potent and selective GCase (glucocerebrosidase) inhibitor, with an IC50 of 29.3 μM and a Ki of 18.5 μM. Glucocerebrosidase-IN-1 can be used for the research of Gaucher disease (GD) and Parkinson’s disease (PD)[1]. |
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| Related Catalog | |
| Target |
IC50: 29.3 ± 1.8 μM (Glucocerebrosidase)[1] |
| In Vitro | Glucocerebrosidase-IN-1 (compound 11a) is able to enhance GCase activity 1.8-fold in fibroblasts bearing the homozygous L444P mutation[1]. |
| References |
| Molecular Formula | C13H27NO3 |
|---|---|
| Molecular Weight | 245.36 |