2420551-38-6

2420551-38-6 structure

Name: ERAP2-IN-1
Chemical Name: ERAP2-IN-1
CAS Number: 2420551-38-6
Molecular Formula: C₂₀H₂₁F₃N₂O₅S
Molecular Weight: 458.45
Catalog: Research Areas Inflammation/Immunology
Create Date: 2022-08-18 17:45:39
Modify Date: 2024-09-16 22:32:00
ERAP2-IN-1 (compound 61) is an uncompetitive ERAP2 inhibitor. ERAP2-IN-1 specifically inhibits the ERAP2 peptide hydrolysis activity, inhibiting Arg-AMC hydrolysis with an IC50 of 27 μM and model peptide hydrolysis with an IC50 of 44 μM[1].

Name	ERAP2-IN-1

Description	ERAP2-IN-1 (compound 61) is an uncompetitive ERAP2 inhibitor. ERAP2-IN-1 specifically inhibits the ERAP2 peptide hydrolysis activity, inhibiting Arg-AMC hydrolysis with an IC50 of 27 μM and model peptide hydrolysis with an IC50 of 44 μM[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Arya R, et al. Phenylsulfamoyl Benzoic Acid Inhibitor of ERAP2 with a Novel Mode of Inhibition. ACS Chem Biol. 2022 Jun 29.

Molecular Formula	C₂₀H₂₁F₃N₂O₅S
Molecular Weight	458.45