1971086-99-3

1971086-99-3 structure

Name: BPN-15477
Chemical Name: BPN-15477
CAS Number: 1971086-99-3
Molecular Formula: C₁₂H₁₀ClN₅
Molecular Weight: 259.69
Catalog: Research Areas Neurological Disease
Create Date: 2022-08-16 12:07:12
Modify Date: 2025-09-18 17:29:02
BPN-15477 is a potent SMC (splicing modulator compound) that restores correct splicing of ELP1 (Elongator complex protein 1) exon 20. BPN-15477 corrects splicing of the ELP1 transcript, significantly increases the level of functional protein in vivo in all tissues, including brain. BPN-15477 can be used for frontotemporal dementia research[1].

Name	BPN-15477

Description	BPN-15477 is a potent SMC (splicing modulator compound) that restores correct splicing of ELP1 (Elongator complex protein 1) exon 20. BPN-15477 corrects splicing of the ELP1 transcript, significantly increases the level of functional protein in vivo in all tissues, including brain. BPN-15477 can be used for frontotemporal dementia research[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Gao D, et al. A deep learning approach to identify gene targets of a therapeutic for human splicing disorders. Nat Commun. 2021 Jun 7;12(1):3332.

Molecular Formula	C₁₂H₁₀ClN₅
Molecular Weight	259.69