Name | BACE1-IN-12 |
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Description | BACE1-IN-12 (compound 7g) is a potent and BBB-penetrated BACE1 inhibitor, with an IC50 of 8.9 µM. BACE1-IN-12 shows selective BuChE (butyrylcholinesterase) inhibitory activity with an IC50 of 3.2 µM. BACE1-IN-12 shows effective antioxidant effect with an IC50 of 10.2 μM (DPPH). BACE1-IN-12 might be served as a potential anti-Alzheimer agent[1]. |
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Related Catalog | |
Target |
IC50: 8.9 ± 0.20 µM (BACE1), 3.2 ± 0.2 µM (BuChE)[1] |
References |
Molecular Formula | C29H28Cl2N6O |
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Molecular Weight | 547.48 |