2428389-65-3

2428389-65-3 structure

Name: AChE-IN-20
Chemical Name: AChE-IN-20
CAS Number: 2428389-65-3
Molecular Formula: C₂₂H₂₀N₈O₆S₂
Molecular Weight: 556.57
Catalog: Signaling Pathways Neuronal Signaling AChE
Create Date: 2022-08-16 16:44:32
Modify Date: 2024-01-09 12:05:04
AChE-IN-20 (compound M26) is a potent AChE inhibitor with IC50 value of 397.32 nM and with Ki value of 335.76 nM. AChE-IN-20 shows inhibition potency against hCA I , hCA II and α-GLY with IC50 values of 84.14, 69.24 and 52.08 nM and with Ki values of 97.86, 76.23 and 57.93 nM, respectively[1].

Name	AChE-IN-20

Description	AChE-IN-20 (compound M26) is a potent AChE inhibitor with IC50 value of 397.32 nM and with Ki value of 335.76 nM. AChE-IN-20 shows inhibition potency against hCA I , hCA II and α-GLY with IC50 values of 84.14, 69.24 and 52.08 nM and with Ki values of 97.86, 76.23 and 57.93 nM, respectively[1].
Related Catalog	Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
References	[1]. Lolak N, et al. Synthesis, characterization, inhibition effects, and molecular docking studies as acetylcholinesterase, α-glycosidase, and carbonic anhydrase inhibitors of novel benzenesulfonamides incorporating 1,3,5-triazine structural motifs. Bioorg Chem. 2020 Jul;100:103897.

Molecular Formula	C₂₂H₂₀N₈O₆S₂
Molecular Weight	556.57