4402-18-0
4402-18-0 structure
- Name: 3,3′-[6,6′-bi-1H-Benzimidazole]-2,2′-diylbis-benzenamine
- Chemical Name: DDRI-18
- CAS Number: 4402-18-0
- Molecular Formula: C26H20N6
- Molecular Weight: 416.48
- Catalog: Signaling Pathways Cell Cycle/DNA Damage DNA/RNA Synthesis
- Create Date: 2022-07-27 10:40:49
- Modify Date: 2025-08-28 07:57:33
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DDRI-18 is a DNA damage response inhibitor that inhibits the non-homologous end-joining (NHEJ) DNA repair process. DDRI-18 is an effective chemosensitizing agent[1].
| Name | DDRI-18 |
|---|---|
| Synonyms |
Benzenamine, 3,3'-[6,6'-bi-1H-benzimidazole]-2,2'-diylbis-
3,3'-[6,6'-bi-1H-Benzimidazole]-2,2'-diylbis-benzenamine MFCD01137750 3,3'-(1H,1'H-5,5'-Bibenzimidazole-2,2'-diyl)dianiline DDRI-18 |
| Description | DDRI-18 is a DNA damage response inhibitor that inhibits the non-homologous end-joining (NHEJ) DNA repair process. DDRI-18 is an effective chemosensitizing agent[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 835.8±75.0 °C at 760 mmHg |
| Molecular Formula | C26H20N6 |
| Molecular Weight | 416.48 |
| Flash Point | 503.4±24.3 °C |
| Exact Mass | 416.174957 |
| LogP | 4.08 |
| Vapour Pressure | 0.0±3.1 mmHg at 25°C |
| Index of Refraction | 1.804 |
| Storage condition | 2-8°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335-H413 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Phrases | 36/37/38 |
| RIDADR | NONH for all modes of transport |