340306-87-8

340306-87-8 structure

Name: SIRT5 inhibitor 2
Chemical Name: SIRT5 inhibitor 2
CAS Number: 340306-87-8
Molecular Formula: C₁₈H₁₂Cl₂N₂O₃S
Molecular Weight: 407.27
Catalog: Signaling Pathways Cell Cycle/DNA Damage Sirtuin
Create Date: 2022-07-01 14:54:39
Modify Date: 2025-08-25 16:15:31
SIRT5 inhibitor 2 (compound 49) is a potent SIRT5 inhibitor with an IC50 value of 2.3 μM. SIRT5 inhibitor 2 has inhibitory activity against the SIRT5-dependent desuccinylation. SIRT5 inhibitor 2 can be used for researching cancer and neurodegenerative diseases[1].

Name	SIRT5 inhibitor 2

Description	SIRT5 inhibitor 2 (compound 49) is a potent SIRT5 inhibitor with an IC50 value of 2.3 μM. SIRT5 inhibitor 2 has inhibitory activity against the SIRT5-dependent desuccinylation. SIRT5 inhibitor 2 can be used for researching cancer and neurodegenerative diseases[1].
Related Catalog	Signaling Pathways >> Epigenetics >> Sirtuin Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Sirtuin Research Areas >> Neurological Disease
Target	SIRT5:2.3 μM (IC50)
References	[1]. Wang Y, et al. Overview of SIRT5 as a potential therapeutic target: Structure, function and inhibitors. Eur J Med Chem. 2022;236:114363.

Molecular Formula	C₁₈H₁₂Cl₂N₂O₃S
Molecular Weight	407.27