2408123-36-2
2408123-36-2 structure
- Name: HDAC-IN-38
- Chemical Name: HDAC-IN-38
- CAS Number: 2408123-36-2
- Molecular Formula: C27H28ClN3O2
- Molecular Weight: 461.98
- Catalog: Signaling Pathways Cell Cycle/DNA Damage HDAC
- Create Date: 2022-07-29 18:45:27
- Modify Date: 2023-01-26 11:20:12
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HDAC-IN-38 (compound 13) is a potent HDAC inhibitor. HDAC-IN-38 shows similar micro-molar inhibitory activity toward HDAC1, 2, 3, 5, 6, and 8. HDAC-IN-38 increases cerebral blood flow (CBF), attenuates cognitive impairment, and improves hippocampal atrophy. HDAC-IN-38 also increases the level of histone acetylation (H3K14 or H4K5)[1].
| Name | HDAC-IN-38 |
|---|
| Description | HDAC-IN-38 (compound 13) is a potent HDAC inhibitor. HDAC-IN-38 shows similar micro-molar inhibitory activity toward HDAC1, 2, 3, 5, 6, and 8. HDAC-IN-38 increases cerebral blood flow (CBF), attenuates cognitive impairment, and improves hippocampal atrophy. HDAC-IN-38 also increases the level of histone acetylation (H3K14 or H4K5)[1]. |
|---|---|
| Related Catalog | |
| Target |
HDAC8:0.533 μM (IC50) HDAC6:1.27 μM (IC50) HDAC3:2.86 μM (IC50) HDAC1:3.82 μM (IC50) HDAC5:6.27 μM (IC50) HDAC2:6.62 μM (IC50) |
| References |
| Molecular Formula | C27H28ClN3O2 |
|---|---|
| Molecular Weight | 461.98 |