2413148-53-3

2413148-53-3 structure

Name: Anticancer agent 61
Chemical Name: Anticancer agent 61
CAS Number: 2413148-53-3
Molecular Formula: C₂₂H₂₂N₃Na₂O₈PS
Molecular Weight: 565.44
Catalog: Research Areas Cancer
Create Date: 2022-07-27 20:19:50
Modify Date: 2025-08-27 09:24:25
Anticancer agent 61 (compound 3v) is an orally active and potent anticancer agent. Anticancer agent 61 shows antiproliferative activity in HepG2, Bel-7402 and MCF-7 cancer cells, with IC50 values of 1.12, 1.97 and 1.08 μM, respectively. Anticancer agent 61 shows effective tumor growth inhibition[1].

Name	Anticancer agent 61

Description	Anticancer agent 61 (compound 3v) is an orally active and potent anticancer agent. Anticancer agent 61 shows antiproliferative activity in HepG2, Bel-7402 and MCF-7 cancer cells, with IC50 values of 1.12, 1.97 and 1.08 μM, respectively. Anticancer agent 61 shows effective tumor growth inhibition[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vivo	Anticancer agent 61 (compound 3v) (BALB/c mice, 0-100 mg/kg, IV, once daily for 14 times) substantially reduces human HepG2 xenograft mouse tumor growth by 54.5% at 50 mg/kg[1].
References	[1]. Liu Y, et al. Synthesis and structure-activity relationship study of water-soluble carbazole sulfonamide derivatives as new anticancer agents. Eur J Med Chem. 2020 Apr 1;191:112181.

Molecular Formula	C₂₂H₂₂N₃Na₂O₈PS
Molecular Weight	565.44