Shanghai Nianxing Industrial Co., Ltd
China
Product Name: TKIM
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Purity: 99.3%
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326921-25-9

326921-25-9 structure

326921-25-9 structure

Name: TKIM
Chemical Name: N'-(4-chlorobenzoyl)-2-(quinolin-2-ylsulfanyl)acetohydrazide
CAS Number: 326921-25-9
Molecular Formula: C₁₈H₁₄ClN₃O₂S
Molecular Weight: 371.84
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Potassium Channel
Create Date: 2022-06-07 19:46:44
Modify Date: 2024-07-18 08:13:40
TKIM is a TREK-1 channel inhibitor with an IC50 of 2.96 μM. TKIM binds to the pocket of the intermediate (IM) state of TREK-1[1].

Name	N'-(4-chlorobenzoyl)-2-(quinolin-2-ylsulfanyl)acetohydrazide

Description	TKIM is a TREK-1 channel inhibitor with an IC50 of 2.96 μM. TKIM binds to the pocket of the intermediate (IM) state of TREK-1[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
References	[1]. Yuqin Ma, et al. Discovery of an Inhibitor for the TREK-1 Channel Targeting an Intermediate Transition State of Channel Gating. J Med Chem. 2020 Oct 8;63(19):10972-10983.

Molecular Formula	C₁₈H₁₄ClN₃O₂S
Molecular Weight	371.84

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