1390616-76-8

1390616-76-8 structure

Name: Aldose reductase-IN-3
Chemical Name: Aldose reductase-IN-3
CAS Number: 1390616-76-8
Molecular Formula: C₁₈H₁₂ClN₃O₂S₂
Molecular Weight: 401.89
Create Date: 2022-05-19 20:56:51
Modify Date: 2025-08-26 22:42:09
Aldose reductase-IN-3 (Compound 5) is a potent and moderately selective inhibitor of aldose reductase (AR) with an IC50 of 3.99 μM. Aldose reductase has recently emerged as a molecular target that is involved in various inflammatory diseases, including sepsis. Aldose reductase-IN-3 has the potential for the research of sepsis[1].

Name	Aldose reductase-IN-3

Description	Aldose reductase-IN-3 (Compound 5) is a potent and moderately selective inhibitor of aldose reductase (AR) with an IC50 of 3.99 μM. Aldose reductase has recently emerged as a molecular target that is involved in various inflammatory diseases, including sepsis. Aldose reductase-IN-3 has the potential for the research of sepsis[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Aldose Reductase Research Areas >> Inflammation/Immunology
References	[1]. Kousaxidis A, et al. Non-acidic bifunctional benzothiazole-based thiazolidinones with antimicrobial and aldose reductase inhibitory activity as a promising therapeutic strategy for sepsis [published online ahead of print, 2021 Aug 4]. Med Chem Res. 2021;1-12.

Molecular Formula	C₁₈H₁₂ClN₃O₂S₂
Molecular Weight	401.89