Aldose reductase-IN-3

Modify Date: 2024-01-03 07:47:46

Aldose reductase-IN-3 Structure
Aldose reductase-IN-3 structure
Common Name Aldose reductase-IN-3
CAS Number 1390616-76-8 Molecular Weight 401.89
Density N/A Boiling Point N/A
Molecular Formula C18H12ClN3O2S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Aldose reductase-IN-3


Aldose reductase-IN-3 (Compound 5) is a potent and moderately selective inhibitor of aldose reductase (AR) with an IC50 of 3.99 μM. Aldose reductase has recently emerged as a molecular target that is involved in various inflammatory diseases, including sepsis. Aldose reductase-IN-3 has the potential for the research of sepsis[1].

 Names

Name Aldose reductase-IN-3

 Aldose reductase-IN-3 Biological Activity

Description Aldose reductase-IN-3 (Compound 5) is a potent and moderately selective inhibitor of aldose reductase (AR) with an IC50 of 3.99 μM. Aldose reductase has recently emerged as a molecular target that is involved in various inflammatory diseases, including sepsis. Aldose reductase-IN-3 has the potential for the research of sepsis[1].
Related Catalog
References

[1]. Kousaxidis A, et al. Non-acidic bifunctional benzothiazole-based thiazolidinones with antimicrobial and aldose reductase inhibitory activity as a promising therapeutic strategy for sepsis [published online ahead of print, 2021 Aug 4]. Med Chem Res. 2021;1-12.

 Chemical & Physical Properties

Molecular Formula C18H12ClN3O2S2
Molecular Weight 401.89