189224-35-9

189224-35-9 structure

Name: Leptin (116-130)
Chemical Name: Leptin (116-130)
CAS Number: 189224-35-9
Molecular Formula: C₆₄H₁₀₈N₁₈O₂₅S
Molecular Weight: 1561.72
Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
Create Date: 2022-04-13 08:00:29
Modify Date: 2025-08-25 17:52:52
Leptin (116-130) is a bioactive leptin fragment. Leptin (116-130) promotes AMPA receptor trafficking to synapses and facilitate activity-dependent hippocampal synaptic plasticity. Leptin (116-130) prevents hippocampal synaptic disruption and neuronal cell death in models of amyloid toxicity. Leptin (116-130) has the potential for the research of Alzheimer's disease (AD)[1].

Name	Leptin (116-130)

Description	Leptin (116-130) is a bioactive leptin fragment. Leptin (116-130) promotes AMPA receptor trafficking to synapses and facilitate activity-dependent hippocampal synaptic plasticity. Leptin (116-130) prevents hippocampal synaptic disruption and neuronal cell death in models of amyloid toxicity. Leptin (116-130) has the potential for the research of Alzheimer's disease (AD)[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
References	[1]. Malekizadeh Y, et al. A Leptin Fragment Mirrors the Cognitive Enhancing and Neuroprotective Actions of Leptin. Cereb Cortex. 2017;27(10):4769-4782.

Molecular Formula	C₆₄H₁₀₈N₁₈O₂₅S
Molecular Weight	1561.72