2716890-91-2

2716890-91-2 structure

Name: CHD1Li 6.11
Chemical Name: CHD1Li 6.11
CAS Number: 2716890-91-2
Molecular Formula: C₂₁H₂₂BrN₅OS
Molecular Weight: 472.40
Catalog: Research Areas Cancer
Create Date: 2022-04-28 04:21:11
Modify Date: 2025-08-25 08:43:03
CHD1Li 6.11 is a potent oncogenic CHD1L inhibitor (IC50=3.3 µM for cat-CHD1L recombinant protein). CHD1Li 6.11 is an orally bioavailable antitumor agent, significantly reducing the tumor volume of CRC xenografts generated from isolated quasi mesenchymal cells (M-phenotype), which possess enhanced tumorigenic properties[1].

Name	CHD1Li 6.11

Description	CHD1Li 6.11 is a potent oncogenic CHD1L inhibitor (IC50=3.3 µM for cat-CHD1L recombinant protein). CHD1Li 6.11 is an orally bioavailable antitumor agent, significantly reducing the tumor volume of CRC xenografts generated from isolated quasi mesenchymal cells (M-phenotype), which possess enhanced tumorigenic properties[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Prigaro BJ, et al. Design, Synthesis, and Biological Evaluation of the First Inhibitors of Oncogenic CHD1L. J Med Chem. 2022;65(5):3943-3961.

Molecular Formula	C₂₁H₂₂BrN₅OS
Molecular Weight	472.40