786706-21-6

786706-21-6 structure

Name: Quin C1
Chemical Name: Quin C1
CAS Number: 786706-21-6
Molecular Formula: C₂₆H₂₇N₃O₄
Molecular Weight: 445.51
Create Date: 2022-03-23 12:01:44
Modify Date: 2024-01-19 17:11:19
Quin C1 is a highly specific and potent agonist for formyl peptide receptor 2 (FPR2/ALX). Quin-C1 significantly reduces the neutrophil and lymphocyte counts in BALF, diminishes expression of TNF-α, IL-1β, KC, and TGF-β1, and decreases collagen deposition in lung tissue. Quin C1 has the potential for the research of lung injury[1].

Name	Quin C1
Synonyms	quin-C1 Benzamide, 4-butoxy-N-[1,4-dihydro-2-(4-methoxyphenyl)-4-oxo-3(2H)-quinazolinyl]- 4-Butoxy-N-[2-(4-methoxyphenyl)-4-oxo-1,4-dihydro-3(2H)-quinazolinyl]benzamide 4-Butoxy-N-[1,4-dihydro-2-(4-methoxyphenyl)-4-oxo-3(2H)-quinazolinyl]benzamide 4-butoxy-N-(2-(4-methoxy-phenyl)-4-oxo-1,4-dihydro-2H-quinazolin-3-yl)-benzamide

Description	Quin C1 is a highly specific and potent agonist for formyl peptide receptor 2 (FPR2/ALX). Quin-C1 significantly reduces the neutrophil and lymphocyte counts in BALF, diminishes expression of TNF-α, IL-1β, KC, and TGF-β1, and decreases collagen deposition in lung tissue. Quin C1 has the potential for the research of lung injury[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. He M, et al. Characterization of Quin-C1 for its anti-inflammatory property in a mouse model of bleomycin-induced lung injury. Acta Pharmacol Sin. 2011;32(5):601-610.