Quin C1

Modify Date: 2024-01-19 17:11:19

Quin C1 Structure
Quin C1 structure
Common Name Quin C1
CAS Number 786706-21-6 Molecular Weight 445.51
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula C26H27N3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Quin C1


Quin C1 is a highly specific and potent agonist for formyl peptide receptor 2 (FPR2/ALX). Quin-C1 significantly reduces the neutrophil and lymphocyte counts in BALF, diminishes expression of TNF-α, IL-1β, KC, and TGF-β1, and decreases collagen deposition in lung tissue. Quin C1 has the potential for the research of lung injury[1].

 Names

Name Quin C1
Synonym More Synonyms

 Quin C1 Biological Activity

Description Quin C1 is a highly specific and potent agonist for formyl peptide receptor 2 (FPR2/ALX). Quin-C1 significantly reduces the neutrophil and lymphocyte counts in BALF, diminishes expression of TNF-α, IL-1β, KC, and TGF-β1, and decreases collagen deposition in lung tissue. Quin C1 has the potential for the research of lung injury[1].
Related Catalog
References

[1]. He M, et al. Characterization of Quin-C1 for its anti-inflammatory property in a mouse model of bleomycin-induced lung injury. Acta Pharmacol Sin. 2011;32(5):601-610.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Molecular Formula C26H27N3O4
Molecular Weight 445.51
Exact Mass 445.200165
LogP 2.79
Index of Refraction 1.645

 Synonyms

quin-C1
Benzamide, 4-butoxy-N-[1,4-dihydro-2-(4-methoxyphenyl)-4-oxo-3(2H)-quinazolinyl]-
4-Butoxy-N-[2-(4-methoxyphenyl)-4-oxo-1,4-dihydro-3(2H)-quinazolinyl]benzamide
4-Butoxy-N-[1,4-dihydro-2-(4-methoxyphenyl)-4-oxo-3(2H)-quinazolinyl]benzamide
4-butoxy-N-(2-(4-methoxy-phenyl)-4-oxo-1,4-dihydro-2H-quinazolin-3-yl)-benzamide