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66522-78-9

66522-78-9 structure
66522-78-9 structure
  • Name: 1-Cyclohexanol-d12
  • Chemical Name: Cyclohexanol-d12
  • CAS Number: 66522-78-9
  • Molecular Formula: C6D12O
  • Molecular Weight: 112.23300
  • Catalog: Research Areas Others
  • Create Date: 2018-10-02 21:38:47
  • Modify Date: 2024-01-02 21:18:02
  • 1-Cyclohexanol-d12 is the deuterium labeled 1-Cyclohexanol[1].

Name Cyclohexanol-d12
Synonyms EINECS 266-389-6
1,1,2,2,3,3,4,4,5,5,6-undecadeuterio-6-deuteriooxycyclohexane
Description 1-Cyclohexanol-d12 is the deuterium labeled 1-Cyclohexanol[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Density 1.059 g/mL at 25ºC
Boiling Point 160-161ºC(lit.)
Melting Point 20-22ºC(lit.)
Molecular Formula C6D12O
Molecular Weight 112.23300
Flash Point 154 °F
Exact Mass 112.16400
PSA 20.23000
LogP 1.31140
Index of Refraction n20/D 1.4608(lit.)
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302 + H332-H315-H335
Precautionary Statements P261
Hazard Codes Xn
Risk Phrases R20/22;R37/38
Safety Phrases S36-S37
WGK Germany 3

~17%

66522-78-9 structure

66522-78-9

Literature: Nam, Wonwoo; Lim, Mi H.; Oh, So-Young; Lee, Jung H.; Lee, Ha J.; Woo, Seung K.; Kim, Cheal; Shin, Woonsup Angewandte Chemie - International Edition, 2000 , vol. 39, # 20 p. 3646 - 3649
Precursor  1

DownStream  1